The best
results come from training utilising the very latest
scientifically proven methods allied with the very best sports
nutritional muscle building supplements and extreme body fat
burners to get you in the very best shape that you can be.
Natural Anabolic Muscle
Builder- 247BodyBuilder is the best and
the STRONGEST LEGAL NATURAL MUSCLE ENHANCER.
If you are serious about building raw muscle size without resorting to
chemicals then you need 247BodyBuilder. This FULL STRENGTH formulation has
been synergistically designed to
Enhance Maximum
Muscle Growth,
Boost Muscle Strength & Development, Improve Performance & Endurance Levels, Strip Away Excess Body Fat
and
Increase Energy & Recovery Levels. Based on an enhanced naturally
anabolic 4:1:1 ratio of potent amino acids, 247Bodybuilder is the No.1
choice for adding large amounts of muscle size, strength and power quickly.
Now with a massive 180 capsules per bottle, if you really want to pack on
pounds of raw muscle quickly then this is the supplement for you.
247BodyBuilder has been specifically formulated for people who
want to have large freaky extra strong muscles without having
to resort to dangerous chemicals. 247BodyBuilder is a blend of
high concentration full strength aminos and natural
testosterone boosters. With this formulation taken in
conjunction with an intensive high intensity training program
you will soon see your muscle size and strength developing.
People will think you are on some secret chemical potion
whereas in truth you are simply taking maximum advantage of
the latest sports nutritional science in order to enhance your
physique to its maximum. This product is designed for maximum
growth and should only be taken if you wish to gain rapid
size, strength and power. Each Bottle contains 180 FULL
STRENGTH capsules - so with 2 bottles you have enough of this
muscle enhancing formulation for some really serious muscle
growth. This product is used mainly by serious bodybuilders
and rugby players but is suitable for anyone who enhanced
muscular development is important.
There are 22 amino acids, without them, all of the metabolic
processes necessary to spark and sustain human life would
simply not be possible. Long chains of amino acids combine to
form up to 55,000 different proteins, and each protein is used
to produce the enzymes, neurotransmitters, and hormones that
support normal growth and functioning of all bodily organs,
including the heart, brain, liver, kidneys, and sex organs.
Amino acids come in two distinct types - essential amino acids
and nonessential amino acids. Essential amino acids cannot be
manufactured in the body (you get these by eating foods that
contain protein), and nonessential amino acids are
manufactured within the body by combining two or more
essential amino acids. However, adequate amounts of dietary
protein are needed to form all 22 amino acids. If you don’t
get enough protein your body won’t have the 9 essential amino
acids it needs to make up the other 13 nonessential amino
acids. This is why we always recommend a full spectrum protein
supplement to muscle building bodybuilders.
Today’s modern Western- style diet is composed largely of
processed foods which often lack in quality protein, for this
reason a good full strength amino acid supplement as listed
above is essential for optimum performance and muscle building
What Are Branched-Chain Amino Acids?
The BCAA Are A Group Of Three Essential Amino Acids:
1. Leucine
2. Isoleucine
3. Valine
The BCAA are different from the other 17 amino acids in that
they are primarily metabolized in skeletal muscle (Layman,
2003) and metabolized at a much lower rate in the liver
(Norton, 2005). The rate limiting enzyme in BCAA catabolism is
Branched Chain Keto Acid Dehydrogenase, which is much more
active in skeletal muscle than in the liver (Norton, 2005).
Point blank, exercise promotes increased BCAA oxidation (Shirmomura
et al., 2004). This increased degradation of BCAA helps
maintain energy homeostasis by providing carbon as a direct
energy source and glucose homeostasis by providing substrates
for the citric-acid cycle and gluconeogenesis.
Amino acids are categorized as glucogenic, ketogenic, or a
combination of glucogenic and ketogenic. A glucogenic amino
acid when metabolized gives rise to pyruvate or other TCA
cycle intermediates that can be used for the production of
glucose through gluconeogenesis.
A ketogenic amino acid is metabolized via the fatty acid
pathway and gives rise to actyl-CoA, a fatty acid precursor.
Leucine is completely ketogenic, valine is completely
glucogenic, and isoleucine is both glucogenic and ketogenic.
Valine and isoleucine can both be used to produce
intermediates for glucose production via gluconeogenesis.
Due to leucine's metabolic properties (discussed below),
increasing attention is being given to it and its metabolism.
Research has shown plasma leucine levels to decrease during
both aerobic and anaerobic exercise (Mero, 1999).
According to Freund and Hanani (2002), "Complete oxidation of
leucine in the muscle yields more adenosine triphosphate
molecules on a molar basis than complete oxidation of
glucose." So leucine can provide skeletal muscle with more ATP
than an equal amount of glucose, which is due to leucine being
completely ketogenic and metabolized via the fatty acid
pathway.
In order to meet the increased demand for BCAA during exercise
the body breaks down muscle tissue to supply additional BCAA.
By supplying the body exogenous BCAA during exercise, one can
meet the increased demand for BCAA oxidation without breaking
down muscle tissue to supply the needed BCAA.
Because BCAA serve as a "fuel" for skeletal muscle,
supplementing with additional BCAA during your workout
improves your performance without the added calories or
insulin spike (which can lead to fat storage) caused by
carbohydrates.
Leucine Stimulates Leptin Expression through mTOR activation
in Adipocytes
Intake of leucine stimulates expression of the hormone leptin
in adipocytes (the primary site of leptin secretion) through
activation of the mTOR pathway (Meijer and Dubbelhuis, 2003).
Leptin is a very complicated hormone; the gist of it is
involved in the regulation of metabolism, body weight, and
appetite.
Leptin secretion is linked with body fat levels; higher body
fat is associated with higher leptin secretion and lower body
fat is associated with lower leptin levels. When you diet and
lose fat, the amount of leptin you secrete decreases, which
makes your body "crave" food in an attempt to bring your body
fat level back up to where the body is comfortable (known as
the body fat "set point").
Leucine has the ability to activate leptin expression and will
cause the body to think it is "fed" or receiving "adequate"
calories, which will keep things running (specifically your
metabolism) smoothly.
BCAA and the Glucose-Alanine Cycle
The BCAA's are involved in maintaining glucose homeostasis
through the glucose-alanine cycle (see figure 1). The glucose-alanine
cycle involves pyruvate (derived from glucose/glycogen) being
transaminated in muscle to form alanine, with the BCAA serving
as the main nitrogen source (donors) for the synthesis of
alanine (Holecek, 2002).
The newly synthesized alanine is released in the blood stream
and sent to the liver where it is converted into glucose
through gluconeogenesis. This glucose can then be sent from
the liver back to the working muscle to be used as fuel.
Supplementing with BCAA allowing your body to create glucose
to use for fuel without the added calories or insulin spike
(which can lead to fat storage) caused by carbohydrates.
There are 22 amino acids, without them, all of the metabolic
processes necessary to spark and sustain human life would
simply not be possible. Long chains of amino acids combine to
form up to 55,000 different proteins, and each protein is used
to produce the enzymes, neurotransmitters, and hormones that
support normal growth and functioning of all bodily organs,
including the heart, brain, liver, kidneys, and sex organs.
Amino acids come in two distinct types - essential amino acids
and nonessential amino acids. Essential amino acids cannot be
manufactured in the body (you get these by eating foods that
contain protein), and nonessential amino acids are
manufactured within the body by combining two or more
essential amino acids. However, adequate amounts of dietary
protein are needed to form all 22 amino acids. If you don’t
get enough protein your body won’t have the 9 essential amino
acids it needs to make up the other 13 nonessential amino
acids. This is why we always recommend a full spectrum protein
supplement to muscle building bodybuilders.
Today’s modern Western- style diet is composed largely of
processed foods which often lack in quality protein, for this
reason a good full strength amino acid supplement as listed
above is essential for optimum performance and muscle building
Research:
1. Biolo, G., B. D. Williams, R. Y. Fleming, and R. R. Wolfe.
Insulin action on muscle protein kinetics and amino acid
transport during recovery after resistance exercise. Diabetes
48: 949-957, 1999.
2. Borsheim, E., K. D. Tipton, S. E. Wolf, and R. R. Wolfe.
Essential amino acids and muscle protein recovery from
resistance exercise. Am.J.Physiol Endocrinol.Metab 283:
E648-E657, 2002.
3. Levenhagen, D. K., J. D. Gresham, M. G. Carlson, D. J.
Maron, M. J. Borel, and P. J. Flakoll. Postexercise nutrient
intake timing in humans is critical to recovery of leg glucose
and protein homeostasis. Am.J.Physiol Endocrinol.Metab 280:
E982-E993, 2001.
4. Rasmussen, B. B., K. D. Tipton, S. L. Miller, S. E. Wolf,
and R. R. Wolfe. An oral essential amino acid-carbohydrate
supplement enhances muscle protein anabolism after resistance
exercise. J.Appl.Physiol 88: 386-392, 2000.
5. Roy, B. D. and M. A. Tarnopolsky. Influence of differing
macronutrient intakes on muscle glycogen resynthesis after
resistance exercise. J.Appl.Physiol 84: 890-896, 1998.
6. Tipton, K. D., A. A. Ferrando, S. M. Phillips, D. Doyle, Jr.,
and R. R. Wolfe. Postexercise net protein synthesis in human
muscle from orally administered amino acids. Am.J.Physiol 276:
E628-E634, 1999.
7. Tipton, K. D., B. B. Rasmussen, S. L. Miller, S. E. Wolf,
S. K. Owens-Stovall, B. E. Petrini, and R. R. Wolfe. Timing of
amino acid-carbohydrate ingestion alters anabolic response of
muscle to resistance exercise. Am.J.Physiol Endocrinol.Metab
281: E197-E206, 2001.
8. Tipton, K. D., E. Borsheim, S. E. Wolf, A. P. Sanford, and
R. R. Wolfe. Acute response of net muscle protein balance
reflects 24-h balance after exercise and amino acid ingestion.
Am.J.Physiol Endocrinol.Metab 284: E76-E89, 2003..